Brock Purdy, QB (SF)

Career night on MNF

Purdy completed 25 of 34 pass attempts for 295 yards, five touchdowns and one interception while taking two carries for 11 yards in Monday's 48-27 rout of the Colts.

Purdy took his game to new heights by throwing five touchdown passes in a game for the first time in his career. The 25-year-old attacked Indianapolis' reeling secondary from the onset, firing three scores to three different receivers on San Francisco's first three possessions Monday. Purdy has been on an absolute heater coming out of the 49ers' bye week, amassing 590 passing yards and eight touchdowns without ever being forced to punt in both starts. The Iowa State Cyclone did lose star TE George Kittle (7-115-1) to an ankle injury in the second half, so Purdy could be missing one of his top weapons against the Bears in Week 17.

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Ricky Pearsall

Ricky Pearsall

WR | SF

To be limited Wednesday

Coach Kyle Shanahan said Pearsall (knee/ankle) will be limited at practice Wednesday, Matt Maiocco of NBC Sports Bay Area reports.

George Kittle

George Kittle

TE | SF

No practice Wednesday

Coach Kyle Shanahan said Kittle (ankle) won't practice Wednesday but "has a chance" to play Sunday against the Bears, Nick Wagoner of ESPN.com reports.

George Kittle

George Kittle

TE | SF

Severity of ankle injury TBD

San Francisco coach Kyle Shanahan said after Monday's 48-27 win against the Colts that it's too early to know the severity of Kittle's ankle injury, Nick Wagoner of ESPN.com reports.